|
rs3218536
|
|
|
0.070 |
GeneticVariation |
BEFREE |
The XRCC2 R188H polymorphism was associated with a modest reduction in EOC risk: OR for heterozygotes was 0.8 (95% confidence interval [CI] = 0.7-1.0) and for rare homozygotes 0.3 (0.1-0.9).
|
15924337 |
2005 |
|
rs3218536
|
|
|
0.070 |
GeneticVariation |
BEFREE |
The aim of the present study was to evaluate the role of SNPs in three genes, XRCC2 (R188H), ERCC2 (K751Q) and CDKN1B (V109G) which are with moderate risk for ovarian cancer susceptibility in Egyptian women.
|
23277402 |
2013 |
|
rs3218536
|
|
|
0.070 |
GeneticVariation |
BEFREE |
The current meta-analysis indicated that the Arg188His polymorphism in the XRCC2 gene might be a risk factor for ovarian cancer.
|
24414483 |
2014 |
|
rs3218536
|
|
|
0.070 |
GeneticVariation |
BEFREE |
Overall, a significant association was found between the Arg188His polymorphism and ovarian cancer risk when all studies were pooled into the meta-analysis (Arg/Arg vs His/His: OR = 1.85, 95%CI = 1.15-3.00; Arg/Arg vs Arg/His: OR = 1.17, 95%CI = 1.03-1.32; dominant model: OR = 0.84, 95%CI = 0.74-0.95; recessive model: OR = 1.69, 95%CI = 1.05-2.70).
|
26400309 |
2015 |
|
rs3218536
|
|
|
0.070 |
GeneticVariation |
BEFREE |
Interestingly, XRCC2 G>A (rs3218536) polymorphism might reduce the risk of ovarian cancer.
|
24599673 |
2014 |
|
rs3218536
|
|
|
0.070 |
GeneticVariation |
BEFREE |
The obtained results indicate that XRCC2 Arg188His and XRCC3 Thr241Met polymorphisms may be positively associated with the incidence of ovarian carcinoma in the population of Polish women.
|
26801223 |
2016 |
|
rs3218536
|
|
|
0.070 |
GeneticVariation |
BEFREE |
In conclusion, this meta-analysis indicates that XRCC2 rs3218536 and ERCC2 rs13181 polymorphisms may not be associated with the risk of OC.
|
27863412 |
2016 |
|
rs25487
|
|
|
0.030 |
GeneticVariation |
BEFREE |
Our study found a significant association between XRCC1 Arg399Gln and XRCC1 Arg194Trp polymorphism and the clinical outcome of ovarian cancer.
|
22983827 |
2013 |
|
rs25487
|
|
|
0.030 |
GeneticVariation |
BEFREE |
Impact of RAD51 G135C and XRCC1 Arg399Gln polymorphisms on ovarian carcinoma risk in Serbian women.
|
26406958 |
2015 |
|
rs25487
|
|
|
0.030 |
GeneticVariation |
BEFREE |
This study indicated that XRCC1 Arg194Trp, Arg280His, and Arg399Gln did not affect OS after platinum-based chemotherapy in OC patients.
|
30407287 |
2018 |
|
rs1799782
|
|
|
0.020 |
GeneticVariation |
BEFREE |
In conclusion, hOGG1 Ser326Cys and XRCC1 Arg194Trp polymorphisms may be regarded as risk factors of ovarian cancer.
|
26124010 |
2015 |
|
rs1799782
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Our study found a significant association between XRCC1 Arg399Gln and XRCC1 Arg194Trp polymorphism and the clinical outcome of ovarian cancer.
|
22983827 |
2013 |
|
rs2228001
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Our results indicated that the XPC Lys939Gln polymorphism may correlate with clinical outcome of patients with epithelial ovarian cancer when treated with platinum-based chemotherapy in Northern China.
|
23621265 |
2013 |
|
rs56318008
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The SNP rs56318008</span> was found to be strongly associated with EOC risk.
|
30457351 |
2018 |
|
rs1222213359
|
|
|
0.020 |
GeneticVariation |
BEFREE |
The study suggested a possible association between the VEGF -1154G/A polymorphism with susceptibility to EOC, but there is no support for an association of the VEGF -460C/T, +936C/T, and -2578C/A polymorphisms with the risk for EOC.
|
20973260 |
2010 |
|
rs1222213359
|
|
|
0.020 |
GeneticVariation |
BEFREE |
None of the five genetic models suggested a significant association between -1154G/A and ovarian cancer risk in the entire study population, or between +936C/T and risk in Asian or Chinese participants.
|
29069849 |
2017 |
|
rs2146323
|
|
|
0.010 |
GeneticVariation |
BEFREE |
VEGF tagSNPs rs3025033 and rs2146323 were not associated with ovarian cancer survival in the Australian sample.
|
20832104 |
2010 |
|
rs3025033
|
|
|
0.010 |
GeneticVariation |
BEFREE |
VEGF tagSNPs rs3025033 and rs2146323 were not associated with ovarian cancer survival in the Australian sample.
|
20832104 |
2010 |
|
rs2228570
|
|
|
0.050 |
GeneticVariation |
BEFREE |
The rs2228570 polymorphism increased the risk of ovarian cancer in Caucasian populations in a dominant genetic model.
|
29239065 |
2018 |
|
rs2228570
|
|
|
0.050 |
GeneticVariation |
BEFREE |
More studies are warranted to assess the association between the VDR rs2228570 polymorphism and ovarian cancer in Asians and Africans.
|
24136742 |
2014 |
|
rs2228570
|
|
|
0.050 |
GeneticVariation |
BEFREE |
This pooled analysis provides further evidence that the VDR rs2228570 polymorphism might influence ovarian cancer susceptibility.
|
20473893 |
2011 |
|
rs2228570
|
|
|
0.050 |
GeneticVariation |
BEFREE |
The homozygote model with the rs2228570 (FokI) polymorphism model appeared to detect the risk of OC in all cases, whereas the heterozygote model with the rs1544410 (BsmI) polymorphism seemed to detect the risk of OC in Caucasian patients.
|
30059751 |
2018 |
|
rs2228570
|
|
|
0.050 |
GeneticVariation |
BEFREE |
The VDR polymorphism FokI (rs2228570) seems to increase the risk of ovarian cancer.
|
29113037 |
2017 |
|
rs1544410
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Moreover, for detecting clinical risk of OC, heterozygote models with the rs1544410 (BsmI) polymorphism is likely the best genetic model for detecting the risk of OC in Caucasian patients.
|
30059751 |
2018 |
|
rs1544410
|
|
|
0.020 |
GeneticVariation |
BEFREE |
The association of ovarian cancer risk with polymorphisms in the vitamin D receptor (VDR) gene, including rs10735810 (FokI), rs11568820 (Cdx-2), rs1544410 (BsmI), rs7975232 (ApaI), rs731236 (TaqI), and BsmI-ApaI-TaqI combined genotypes, was examined among 313 women with epithelial ovarian carcinoma and 574 controls.
|
18086759 |
2007 |